Daflon General Information
Daflon (generic; brand names include: Detralex / Arvenum 500 / Alvenor / Ardium / Capiven / Elatec / Venitol) is highly effective in the treatment of chronic hemorrhoidal disease. It significantly improves subjective symptoms and objective signs eg, anal discomfort, pain, redness, anal discharge, proctitis, tenesmus, pruritus, erythema and bleeding. Daflon 500 mg also significantly reduces the frequency, severity and duration of acute hemorrhoidal attacks by a chronic treatment.
Daflon 500 mg is phlebotonic: It reinforces venous tone by prolonging the activity of parietal noradrenaline. Thus, Daflon 500 mg decreases venous capacitance, venous distensibility and venous emptying time.
Daflon 500 mg protects the microcirculation by fighting the microcirculation-damaging process; it combats venous inflammation by decreasing leukocyte activation, and as a consequence, by inhibiting the release of inflammatory mediators, principally free radicals and prostaglandins. Thus, Daflon 500 mg normalizes capillary permeability and strengthens capillary resistance.
Daflon 500 mg acts on the lymphatic system: It improves lymphatic drainage by increasing lymph flow and lymph oncotic pressure. This action on the lymphatic system associated with a phlebotonic and vasculoprotective effect, explains the activity of Daflon 500 mg on CVI-associated edema.
Double-blind, placebo-controlled studies have demonstrated Daflon 500 mg's efficacy on chronic venous insufficiency. Daflon 500 mg significantly improves disabling symptoms of venous insufficiency which affect everyday active life: Heavy legs, pain, heat sensation, edema, functional impairment and nocturnal cramps.
In addition to conventional compression therapy, Daflon 500 mg has also demonstrated to cure 3 times as many venous leg ulcers as placebo, and to accelerate their complete healing.
Daflon 500 mg is a phlebotonic drug and a vascular protecting agent.
The efficacy of Daflon 500 mg is accounted for by its specific action on the principal elements of venous disease.
Patients taking Daflon for impaired venous circulation should be inform to follow a healthy life-style, reduce excessive body weight and avoid prolonged exposure to the sun, wearing stockings that improve blood circulation. Follow the directions for using this medicine provided by your doctor. Take Daflon exactly as directed.
Daflon 500mg should not be used by patients who are hypersensitive to any of its substance. Your health care provide will evaluate your compatibility with Daflon (Detralex) 500mg prior to prescription. Make sure to inform your doctor of your medical history and the other drugs you are presently taking.
Active ingredient: micronized purified flavonoid fraction containing 90% diosmin and 10% other flavonoids expressed as hesperidin.